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40x water immersion lens  (Scientifica)

 
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    Structured Review

    Scientifica 40x water immersion lens
    40x Water Immersion Lens, supplied by Scientifica, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/40x water immersion lens/product/Scientifica
    Average 86 stars, based on 1 article reviews
    40x water immersion lens - by Bioz Stars, 2026-05
    86/100 stars

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    Focal Tsc2 knockout (fTSC2 KO) mice have decreased somatostatin and parvalbumin cells in the cortex. (A) Tissue from control and fTSC2 KO mice were labeled with antibodies for somatostatin (SST), mCherry, and parvalbumin (PV). Scale bars = 100 (left, 10X) and 50 μm <t>(40X).</t> (B) Parvalbumin (PV) and Somatostatin (SST) interneuron densities were decreased in fTSC2 KO mice compared to controls ( p < 0.05). (C) PV cell densities were decreased in the fTSC2 KO mice compared to controls, particularly in regions 3–8 ( p < 0.05 or p < 0.01, as indicated). (D) Inhibitory cell densities were not correlated with seizures. (E) SST cell densities were decreased in the fTSC2 KO mice compared to controls, particularly in regions 4–6, and 8 ( p < 0.05 or p < 0.01, as indicated). *, p < 0.05; **, p < 0.01.
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    Image Search Results


    Focal Tsc2 knockout (fTSC2 KO) mice have decreased somatostatin and parvalbumin cells in the cortex. (A) Tissue from control and fTSC2 KO mice were labeled with antibodies for somatostatin (SST), mCherry, and parvalbumin (PV). Scale bars = 100 (left, 10X) and 50 μm (40X). (B) Parvalbumin (PV) and Somatostatin (SST) interneuron densities were decreased in fTSC2 KO mice compared to controls ( p < 0.05). (C) PV cell densities were decreased in the fTSC2 KO mice compared to controls, particularly in regions 3–8 ( p < 0.05 or p < 0.01, as indicated). (D) Inhibitory cell densities were not correlated with seizures. (E) SST cell densities were decreased in the fTSC2 KO mice compared to controls, particularly in regions 4–6, and 8 ( p < 0.05 or p < 0.01, as indicated). *, p < 0.05; **, p < 0.01.

    Journal: Frontiers in Molecular Neuroscience

    Article Title: Focal postnatal deletion of Tsc2 causes epilepsy

    doi: 10.3389/fnmol.2025.1686023

    Figure Lengend Snippet: Focal Tsc2 knockout (fTSC2 KO) mice have decreased somatostatin and parvalbumin cells in the cortex. (A) Tissue from control and fTSC2 KO mice were labeled with antibodies for somatostatin (SST), mCherry, and parvalbumin (PV). Scale bars = 100 (left, 10X) and 50 μm (40X). (B) Parvalbumin (PV) and Somatostatin (SST) interneuron densities were decreased in fTSC2 KO mice compared to controls ( p < 0.05). (C) PV cell densities were decreased in the fTSC2 KO mice compared to controls, particularly in regions 3–8 ( p < 0.05 or p < 0.01, as indicated). (D) Inhibitory cell densities were not correlated with seizures. (E) SST cell densities were decreased in the fTSC2 KO mice compared to controls, particularly in regions 4–6, and 8 ( p < 0.05 or p < 0.01, as indicated). *, p < 0.05; **, p < 0.01.

    Article Snippet: All imaging was conducted at the Bio-Imaging and Analysis Facility at Cincinnati Children’s Hospital Medical Center ( RRID:SCR_022628 ) using a Nikon Eclipse Ni-E upright microscope with a 4X (NA 0.20) and 10X (NA 0.45) air objectives or a Nikon A1R confocal microscope equipped with 10X air (NA 0.45), 20X water-immersion (NA 0.95, resolution 0.62 μm/px), and 40X water-immersion (NA 1.15, resolution 0.31 μm/px) objectives (Nikon Instruments Inc.; RRID:SCR_020317 ).

    Techniques: Knock-Out, Control, Labeling